E-CAM-S: Electroencephalographic Confusion Assessment Method Severity Score
2022An automated 0-1 research estimate of delirium and encephalopathy severity derived from quantitative frontal EEG. It is a development-stage physiological model rather than a routine bedside form.
Classification
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Tool and original sources
This record describes a method rather than a downloadable bedside form. The main source is linked below.
Original paper
- Principal sourcevan Sleuwen M, Sun H, Eckhardt C, Neelagiri A, Tesh RA, Westmeijer M, et al. Physiological Assessment of Delirium Severity: The Electroencephalographic Confusion Assessment Method Severity Score (E-CAM-S). Critical care medicine. 2022;50(1):e11-e19. doi: 10.1097/CCM.0000000000005224. PMID: 34582420.
This is the principal published source for E-CAM-S itself. It is the main source for the method, its intended use and the evidence available at publication.
At a glance
- Purpose
- Measurement of delirium severity
- Population
- Adults undergoing clinical EEG for altered mental status
- Setting
- General / acute hospital, Intensive care
- Time
- 20-60 min routine EEG or a 1-hour long-term-monitoring segment, plus automated processing
- Score or threshold
- No clinical diagnostic threshold
Format: The research pipeline used four frontal bipolar channels, 298 time- and frequency-domain features and four across-epoch summaries, then fitted a LASSO-penalised ordinal learning-to-rank model against CAM-S 0-7 values.
Evidence
Reported sensitivity and specificity
Correlation with CAM-S was 0.68 in the full cohort and 0.52 after excluding coma; AUC for non-delirious versus delirious was 0.70.
More evidence and citation details
- Full name
- Electroencephalographic Confusion Assessment Method Severity Score
- Evidence summary
- derivation-and-internal-cross-validation
- Citation
- van Sleuwen M, Sun H, Eckhardt C, et al. Physiological Assessment of Delirium Severity: The Electroencephalographic Confusion Assessment Method Severity Score (E-CAM-S) Critical Care Medicine. 2022;50(1):e11-e19. PMID 34582420
Copyright and reuse
- Version
- E-CAM-S research model and BDSP project v1.0; source model published 2022
- Information checked
- 2026-07-19
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Sources checked 2026-07-29. How profiles are prepared.