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DRS-R-98: Delirium Rating Scale-Revised-98

2001

A trained-clinician 16-item instrument comprising a 13-item severity score and three additional diagnostic items. It supports detailed diagnosis, phenomenology and longitudinal severity measurement rather than rapid screening.

At a glance

Purpose
Measurement of delirium severity
Population
Adult
Setting
General / acute hospital
Time
approximately 15 min, plus collateral and record review when required
Items
16
Score or threshold
Cut-offs by comparison group

Format: The instrument records 16 scored items or observations. This site classifies it under measurement of delirium severity and detailed phenomenological and/or neuropsychological assessment. It is intended for adult use in General / acute hospital. The stated administration time is approximately 15 min, plus collateral and record review when required. The published result is recorded using Cut-offs by comparison group.

  • Strengths: Broad symptom coverage with separate severity and total scores; suited to detailed and longitudinal assessment
  • Limitations: Requires clinician training, direct assessment and often collateral or record information; reported diagnostic thresholds vary by population and comparator, especially in dementia. It is not a brief screening test or a stand-alone diagnosis

Primary validation papers

10 identified diagnostic-accuracy papers

Other forms of validation are described in the evidence section. What is counted?

Large-scale clinical implementation

None identified in the scoped review.

None identified in the selected profile sources and the Penfold general-hospital review. This is not a completed search of all settings or later papers.

Training and instructions

  • DRS-R-98 general instructions. Public scoring and administration instructions hosted by the Dementia Collaborative Research Centres. Read with the current instrument and permission conditions.
  • DRS-R-98 form. Public instrument material checked on 5 September 2026. Follow the source’s version and permission conditions.
Start here

Tool and original sources

View a copy of the DRS-R-98 hosted by the Dementia Centre for Research Collaboration. The scale is not reproduced here.

Original and selected diagnostic-accuracy papers

  • Original paperTrzepacz PT, Mittal D, Torres R, Kanary K, Norton J, Jimerson N. Validation of the Delirium Rating Scale-revised-98: comparison with the delirium rating scale and the cognitive test for delirium. The Journal of neuropsychiatry and clinical neurosciences. 2001;13(2):229-42. doi: 10.1176/jnp.13.2.229. PMID: 11449030.

    The original validation assessed 68 participants across five diagnostic groups using the 16-item total score and 13-item severity score. Depending on threshold and comparator, total-score sensitivity ranged from 91% to 100% and specificity from 85% to 100%; PubMed lists a published erratum.

  • Selected diagnostic-accuracy studyKato M, Kishi Y, Okuyama T, Trzepacz PT, Hosaka T. Japanese version of the Delirium Rating Scale, Revised-98 (DRS-R98-J): reliability and validity. Psychosomatics. 2010;51(5):425-31. doi: 10.1176/appi.psy.51.5.425. PMID: 20833942.

    This diagnostic-accuracy study evaluated DRS-R-98 in a Japanese medically ill inpatient consultation population against independent psychiatric diagnosis separating delirium from dementia and other non-delirium states. It reported sensitivity of 98% and specificity of 94% in 81 psychiatric-consultation medical/surgical inpatients; 48 delirium and 33 non-delirium.

Multiple DTA studies identifiedCore instrument family
Classification

Classification

A tool may belong to more than one category. Select a linked category to see other relevant profiles.

Evidence

Diagnostic-accuracy evidenceMultiple DTA studies identified

Reported sensitivity and specificity

91–100%
Sensitivity
85–100%
Specificity

Original 2001 validation in 68 participants across five diagnostic groups: total-score sensitivity ranged from 91% to 100% and specificity from 85% to 100%, depending on threshold and comparator. PubMed lists a published erratum.

Expanded evidence profile

What the broader evidence shows

Interpretation: DRS-R-98 is a trained-clinician instrument with both a 13-item severity score and a 16-item total score that can support diagnosis and detailed phenomenology. Validation is substantial and multilingual, but thresholds vary with population and comparator; it is not a rapid screening tool or a substitute for clinical diagnosis.

Evidence snapshots

  • Original validation (2001): Across 68 participants in five diagnostic groups, reported total-score sensitivity ranged from 91% to 100% and specificity from 85% to 100%, depending on threshold and comparator.
  • Portuguese validation (2008): In 64 participants across five groups, a total-score threshold of 20 yielded 92.6% sensitivity and 94.6% specificity.
  • Japanese validation (2010): In 81 participants, a total-score threshold of 14.5 yielded 98% sensitivity and 94% specificity overall, but specificity fell to 75% in the dementia comparison.
  • Review-level position (2019-2021): Two broad reviews identified DRS-R-98 as a notable severity and identification instrument, but neither produced a tool-specific pooled sensitivity or specificity estimate.

These results come from different populations and workflows and should not be averaged or treated as interchangeable.

8 selected PubMed-indexed papers, 2001–2024
  1. 2001Original validation study
    Trzepacz PT, Mittal D, Torres R, Kanary K, Norton J, Jimerson N. Validation of the Delirium Rating Scale-Revised-98: comparison with the Delirium Rating Scale and the Cognitive Test for Delirium. J Neuropsychiatry Clin Neurosci. 2001;13(2):229-242. doi: 10.1176/jnp.13.2.229. PMID: 11449030.

    The original validation assessed 68 participants across delirium, dementia, schizophrenia, depression and other groups using the 16-item total score and 13-item severity score. Depending on threshold and comparator, total-score sensitivity ranged from 91% to 100% and specificity from 85% to 100%; PubMed lists a published erratum in the following issue.

    PubMed · PMID 11449030 ↗
  2. 2008Diagnostic-accuracy study
    de Negreiros DP, da Silva Meleiro AM, Furlanetto LM, Trzepacz PT. Portuguese version of the Delirium Rating Scale-Revised-98: reliability and validity. Int J Geriatr Psychiatry. 2008;23(5):472-477. doi: 10.1002/gps.1906. PMID: 17922493.

    This Portuguese validation included 64 participants across five diagnostic groups and used two independent blinded raters. A total-score threshold of 20 yielded 92.6% sensitivity and 94.6% specificity, with an area under the curve of 0.99.

    PubMed · PMID 17922493 ↗
  3. 2010Diagnostic-accuracy study
    Kato M, Kishi Y, Okuyama T, Trzepacz PT, Hosaka T. Japanese version of the Delirium Rating Scale, Revised-98 (DRS-R98-J): reliability and validity. Psychosomatics. 2010;51(5):425-431. doi: 10.1176/appi.psy.51.5.425. PMID: 20833942.

    The Japanese validation included 81 participants, of whom 48 had delirium and 33 did not, and found high inter-rater reliability. At a total-score threshold of 14.5 sensitivity was 98% and specificity 94% overall, although specificity was 75% when delirium was compared specifically with dementia.

    PubMed · PMID 20833942 ↗
  4. 2011Diagnostic-accuracy study
    Lee Y, Ryu J, Lee J, et al. Korean version of the Delirium Rating Scale-Revised-98: reliability and validity. Psychiatry Investig. 2011;8(1):30-38. doi: 10.4306/pi.2011.8.1.30. PMID: 21519534.

    This Korean validation included 157 participants: 69 with delirium, 29 with dementia, 32 with schizophrenia and 27 with other disorders. The total-score area under the curve was 0.948 overall and 0.873 against dementia, with high internal consistency and inter-rater reliability but threshold-dependent classification.

    PubMed · PMID 21519534 ↗
  5. 2015Diagnostic-accuracy study
    Sepulveda E, Franco JG, Trzepacz PT, et al. Performance of the Delirium Rating Scale-Revised-98 Against Different Delirium Diagnostic Criteria in a Population With a High Prevalence of Dementia. Psychosomatics. 2015;56(5):530-541. doi: 10.1016/j.psym.2015.03.005. PMID: 26278338.

    This study tested DRS-R-98 in 125 participants, 85 with dementia, and found that only 19 of 36 delirium cases met every diagnostic system examined. Areas under the curve ranged from 0.905 to 0.929 and optimal total-score thresholds varied slightly by diagnostic system, demonstrating reference-standard effects in dementia-rich populations.

    PubMed · PMID 26278338 ↗
  6. 2019Systematic review
    Jones RN, Cizginer S, Pavlech L, et al. Assessment of Instruments for Measurement of Delirium Severity: A Systematic Review. JAMA Intern Med. 2019;179(2):231-239. doi: 10.1001/jamainternmed.2018.6975. PMID: 30556827.

    This review screened 9,409 records and evaluated 42 delirium-severity instruments, identifying six leading measures that included the DRS family. It assessed psychometric and clinical utility rather than pooling DRS-R-98 diagnostic sensitivity and specificity, so it supports instrument standing rather than a single accuracy estimate.

    PubMed · PMID 30556827 ↗
  7. 2021Systematic review
    Helfand BKI, D'Aquila ML, Tabloski P, et al. Detecting Delirium: A Systematic Review of Identification Instruments for Non-ICU Settings. J Am Geriatr Soc. 2021;69(2):547-555. doi: 10.1111/jgs.16879. PMID: 33135780.

    This non-intensive-care review examined 75 reviews covering 30 instruments and identified DRS-R-98 among four notable tools based on citations, validation methods and DSM-5 coverage. The review did not calculate a DRS-R-98-specific pooled sensitivity or specificity and therefore does not remove the need to consider population and threshold.

    PubMed · PMID 33135780 ↗
  8. 2024Clinical validation study
    Almuhairi ES, Badejo M, Peer A, Pitkanen M, McKenzie CA. The Validity and Applicability of the Revised Delirium Rating Scale (DRS-R98) for Delirium Severity Assessment in a Critical Care Setting. J Intensive Care Med. 2024;39(3):240-249. doi: 10.1177/08850666231199986. PMID: 37670545.

    This preliminary critical-care study assessed severity in 22 patients who already had delirium, comparing clinical scoring with scoring reconstructed from records. Correlations were about 0.63 and internal consistency was high, but the small sample, limited inter-rater subset and lengthy information gathering make this severity evidence rather than a diagnostic-accuracy validation.

    PubMed · PMID 37670545 ↗

This is a selected evidence overview, not a systematic review. It prioritises the original validation, four informative diagnostic validations, two broad systematic reviews and a recent critical-care severity study; all eight records were checked in PubMed and DOI-bearing papers were checked in Scite on 31 August 2026. PubMed lists a published erratum for the original article, which is flagged rather than silently ignored.

More evidence and citation details
Full name
Delirium Rating Scale-Revised-98
Also known as
DRS-R-98, Delirium Rating Scale Revised 98, DRS-R98
Evidence summary
Multiple validation studies and systematic reviews; no robust tool-specific pooled diagnostic estimate
Diagnostic-accuracy evaluations
10
Reference standard
Clinical diagnosis (5 groups)
Reliability
High inter-rater; high internal consistency
Citation
Trzepacz PT, Mittal D, Torres R, Kanary K, Norton J, Jimerson N Validation of the Delirium Rating Scale-revised-98: comparison with the delirium rating scale and the cognitive test for delirium The Journal of neuropsychiatry and clinical neurosciences. 2001;13(2):229-42. PMID 11449030

Primary validation studies

Distinct primary publications from the current diagnostic-accuracy audit. Reviews and repeated evaluations within one paper are not counted again. Overlapping cohorts have not all been reconciled. Read the counting rules and limitations.

Open 10 identified papers
  1. Trzepacz PT, Mittal D, Torres R, Kanary K, Norton J, Jimerson N (2001). Validation of the Delirium Rating Scale-revised-98: comparison with the delirium rating scale and the cognitive test for delirium. The Journal of neuropsychiatry and clinical neurosciences.

    Reference category: other comparator or secondary accuracy evidence.

  2. Franco JG, Mejía MA, Ochoa SB, Ramírez LF, Bulbena A, Trzepacz P (2007). [Delirium rating scale-revised-98 (DRS-R-98): Colombian adaptation of the Spanish version]. Actas espanolas de psiquiatria.

    Reference category: independent clinical reference.

  3. de Negreiros DP, da Silva Meleiro AM, Furlanetto LM, Trzepacz PT (2008). Portuguese version of the Delirium Rating Scale-Revised-98: reliability and validity. International journal of geriatric psychiatry.

    Reference category: independent clinical reference.

  4. Huang MC, Lee CH, Lai YC, Kao YF, Lin HY, Chen CH (2009). Chinese version of the Delirium Rating Scale-Revised-98: reliability and validity. Comprehensive psychiatry.

    Reference category: other comparator or secondary accuracy evidence.

  5. Kato M, Kishi Y, Okuyama T, Trzepacz PT, Hosaka T (2010). Japanese version of the Delirium Rating Scale, Revised-98 (DRS-R98-J): reliability and validity. Psychosomatics.

    Reference category: independent clinical reference.

  6. Lee Y, Ryu J, Lee J, Kim HJ, Shin IH, Kim JL, Trzepacz PT (2011). Korean version of the delirium rating scale-revised-98: reliability and validity. Psychiatry investigation.

    Reference category: other comparator or secondary accuracy evidence.

  7. Janssen NJ, Tan EY, Staal M, Janssen EP, Leroy PL, Lousberg R, van Os J, Schieveld JN (2011). On the utility of diagnostic instruments for pediatric delirium in critical illness: an evaluation of the Pediatric Anesthesia Emergence Delirium Scale, the Delirium Rating Scale 88, and the Delirium Rating Scale-Revised R-98. Intensive care medicine.

    Reference category: independent clinical reference.

  8. Mehmet Alper Cinar, Kamil Nahit Ozmenler, Aytekin Ozsahin, Paula T. Trzepacz (2014). Reliability and validity of the Turkish translation of the Delirium Rating Scale-Revised-98. Dusunen Adam: The Journal of Psychiatry and Neurological Sciences.

    Reference category: independent clinical reference.

  9. Whittamore KH, Goldberg SE, Gladman JR, Bradshaw LE, Jones RG, Harwood RH (2014). The diagnosis, prevalence and outcome of delirium in a cohort of older people with mental health problems on general hospital wards. International journal of geriatric psychiatry.

    Reference category: other comparator or secondary accuracy evidence.

  10. Sepulveda E, Franco JG, Trzepacz PT, Gaviria AM, Viñuelas E, Palma J, Ferré G, Grau I, Vilella E (2015). Performance of the Delirium Rating Scale-Revised-98 Against Different Delirium Diagnostic Criteria in a Population With a High Prevalence of Dementia. Psychosomatics.

    Reference category: other comparator or secondary accuracy evidence.

Copyright and reuse
Version
DRS-R-98 form carrying © Trzepacz 1998 and a reproduced-with-permission notice
Information checked
2026-07-19

Instrument-specific terms apply. See the access and copyright policy or send a correction.

Base clinical review: 2026-08-31. Instrument description source check: 2026-09-05. Scope and limitations.