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PIPRA: Pre-Interventional Preventive Risk Assessment

2023

An international preoperative model estimating postoperative delirium risk before selected surgery. It is a risk calculation, not a test for delirium, and commercial relationships require transparent disclosure.

Classification

Classification

Future-risk prediction

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Tool and original sources

This record describes a method rather than a downloadable bedside form. The main source is linked below.

Original paper

  • Principal sourceDodsworth BT, Reeve K, Falco L, Hueting T, Sadeghirad B, Mbuagbaw L, et al. Development and validation of an international preoperative risk assessment model for postoperative delirium. Age and ageing. 2023;52(6). doi: 10.1093/ageing/afad086. PMID: 37290122.

    This paper reports the development and initial validation of PIPRA. It is the main source for the method, its intended use and the evidence available at publication.

    Article PDF: CC BY-NC. This licence applies to the article PDF and does not grant rights to reproduce the tool.

No eligible DTA study identifiedRelated context

At a glance

Purpose
Future-risk prediction
Population
Adults undergoing non-cardiac, non-intracranial surgery
Setting
Perioperative
Time
preoperative digital calculation; completion time not reported
Score or threshold
No single universal threshold established for all settings

Evidence

Evidence maturityNo eligible DTA study identified

Reported sensitivity and specificity

not applicable
Sensitivity
not applicable
Specificity

AUROC was 0.80 with C-reactive protein and 0.79 without it in internal validation, and 0.74 in external validation.

More evidence and citation details
Full name
Pre-Interventional Preventive Risk Assessment
Evidence summary
multicohort-development-and-external-validation
Citation
Dodsworth BT, et al. Development and validation of an international preoperative risk assessment model for postoperative delirium Age and Ageing. 2023;52(6):afad086. PMID 37290122
Copyright and reuse
Information checked
2026-07-19

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Sources checked 2026-07-29. How profiles are prepared.