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CAM-ICU Plus

2026

A single-study acute-ischaemic-stroke algorithm that supplements CAM-ICU classification with assessment of psychomotor change. It is not yet an established ICU instrument or externally validated scale.

At a glance

Purpose
Episodic assessment
Population
Adult
Setting
General / acute hospital, Stroke unit
Time
not independently established
Score or threshold
CAM-ICU Plus positive

Format: CAM-ICU Plus is a study-defined classification variant rather than a separately published questionnaire. Its exact operational rule should be read in the source; it is not reproduced here.

Primary validation papers

1 identified diagnostic-accuracy paper

Other forms of validation are described in the evidence section. What is counted?

Large-scale clinical implementation

Not yet reviewed.

A focused implementation review has not yet been completed for this profile.

Training and instructions

Public training resources have not yet been confirmed in this review. Check the linked developer or original source for instructions.

Start here

Tool and original sources

This record describes a method rather than a downloadable bedside form. The main source is linked below.

Read the full paper ↗

Original paper

  • Original paperSomarajan D, Prakash R, Chellamma J, Shelley NS, Anand A, James TG, et al. Diagnostic Accuracy of CAM-ICU and ICDSC for Detection of Early Delirium in Acute Ischemic Stroke: A Cross-sectional Study. Annals of Indian Academy of Neurology. 2026;29(1):59-66. doi: 10.4103/aian.aian_925_25. PMID: 41559862.

    This paper reports the original validation of CAM-ICU Plus. It reported sensitivity of 79.24% and specificity of 91.89% against a DSM-5 clinical assessment.

    Open PubMed ↗Download article PDF ↓

    Article PDF: CC BY-NC-ND. This licence applies to the article PDF and does not grant rights to reproduce the tool.

One DTA study identifiedEmerging clinical record
Classification

Classification

Episodic assessment

A tool may belong to more than one category. Select a linked category to see other relevant profiles.

Evidence

Diagnostic-accuracy evidenceOne DTA study identified

Reported sensitivity and specificity

Headline metric source

Original/source study · 2026; pmid:41559862

Denominator
Reported source unit: 164 (analysis unit not fully reconciled)
Reference standard
Blinded DSM-5 delirium assessment by a separate diagnostic team
79.24%
Sensitivity
91.89%
Specificity

Earliest DTA evaluation identified in the current audit; see the linked source and methodological caveats.

More evidence and citation details
Full name
CAM-ICU Plus
Also known as
CAM-ICU plus psychomotor changes
Related profiles
CAM-ICU
Evidence summary
single-DTA
Diagnostic-accuracy evaluations
1
Reference standard
Blinded DSM-5 delirium assessment by a separate diagnostic team
Citation
Somarajan D, Prakash R, Chellamma J, Shelley NS, Anand A, James TG, Mangalanandan N, Mathews AM, Fletcher NE Diagnostic Accuracy of CAM-ICU and ICDSC for Detection of Early Delirium in Acute Ischemic Stroke: A Cross-sectional Study Annals of Indian Academy of Neurology. 2026;29(1):59-66. PMID 41559862
Download RIS ↗ Download BibTeX ↗

Primary validation studies

Distinct primary publications from the current diagnostic-accuracy audit. Reviews and repeated evaluations within one paper are not counted again. Overlapping cohorts have not all been reconciled. Read the counting rules and limitations.

Open 1 identified paper
  1. Somarajan D, Prakash R, Chellamma J, Shelley NS, Anand A, James TG, Mangalanandan N, Mathews AM, Fletcher NE (2026). Diagnostic Accuracy of CAM-ICU and ICDSC for Detection of Early Delirium in Acute Ischemic Stroke: A Cross-sectional Study. Annals of Indian Academy of Neurology.

    Reference category: independent clinical reference.

Copyright and reuse
Information checked
2026-07-19

Instrument-specific terms apply. See the access and copyright policy or send a correction.

Base clinical review: 2026-07-29. Instrument description source check: 2026-09-05. Scope and limitations.