CAM-ICU Plus

2026

A single-study acute-ischaemic-stroke algorithm that supplements CAM-ICU classification with assessment of psychomotor change. It is not yet an established ICU instrument or externally validated scale.

Classification

Episodic assessment

A tool may belong to more than one category. Select a linked category to see other relevant profiles.

Start here

Tool and original sources

This record describes a method rather than a downloadable bedside form. The main source is linked below.

Read the full paper ↗

Original paper

Original paperSomarajan D, Prakash R, Chellamma J, Shelley NS, Anand A, James TG, et al. Diagnostic Accuracy of CAM-ICU and ICDSC for Detection of Early Delirium in Acute Ischemic Stroke: A Cross-sectional Study. Annals of Indian Academy of Neurology. 2026;29(1):59-66. doi: 10.4103/aian.aian_925_25. PMID: 41559862.
This paper reports the original validation of CAM-ICU Plus. It reported sensitivity of 79.24% and specificity of 91.89% against a DSM-5 clinical assessment.
Open PubMed ↗Download article PDF ↓
Article PDF: CC BY-NC-ND. This licence applies to the article PDF and does not grant rights to reproduce the tool.

One DTA study identifiedEmerging clinical record

At a glance

Purpose: Episodic assessment
Population: Adult
Setting: General / acute hospital, Stroke unit
Time: not independently established
Score or threshold: CAM-ICU Plus positive

Format: CAM-ICU Plus is a study-defined classification variant rather than a separately published questionnaire. Its exact operational rule should be read in the source; it is not reproduced here.

Evidence

Evidence maturityOne DTA study identified

Reported sensitivity and specificity

Headline metric source

Original/source study · 2026 — pmid:41559862

Denominator: Reported source unit: 164 (analysis unit not fully reconciled)
Reference standard: Blinded DSM-5 delirium assessment by a separate diagnostic team

79.24%

Sensitivity

91.89%

Specificity

Earliest DTA evaluation identified in the current audit; see the linked source and methodological caveats.

More evidence and citation details

Full name: CAM-ICU Plus
Also known as: CAM-ICU plus psychomotor changes
Related profiles: CAM-ICU
Evidence summary: single-DTA
Diagnostic-accuracy studies: 1
Reference standard: Blinded DSM-5 delirium assessment by a separate diagnostic team
Citation: Somarajan D, Prakash R, Chellamma J, Shelley NS, Anand A, James TG, Mangalanandan N, Mathews AM, Fletcher NE Diagnostic Accuracy of CAM-ICU and ICDSC for Detection of Early Delirium in Acute Ischemic Stroke: A Cross-sectional Study Annals of Indian Academy of Neurology. 2026;29(1):59-66. PMID 41559862

Download RIS ↗ Download BibTeX ↗

Information checked: 2026-07-19

Instrument-specific terms apply. See the access and copyright policy or send a correction.

Sources checked 2026-07-29. How profiles are prepared.